Therapy

I was seen by my pdoc today and he confirmed that I’m experiencing a mixed mood. I have bipolar disorder and am still working up to a therapeutic dose of Lamictal(I’m at 75mg)
Since I’ve been experiencing some severe depression as well as insomnia and racing thoughts he added a very small dosage(12.5mg) of Seroquel to help further stabalize my moods and sleep. Has anyone had this done to help with their mixed mood? Did it work? If not what did work? Thanks in advance.
Thanks! I take the Lamictal in the am as well. I hope the Seroquel works. I’m only worried now if it works that well I won’t be ablet o wake up early enough to go to my therapist tomorrow.

Hi. I was diagnosed by a psychiatrist with bipolar after an antidepressants flipped me manic. My main problem has been mixed states which I mistook for depression, a couple instances of something more like mixed mania, and for the last year rapid cycling. I was started on Lamictal for the lows, Trileptal for the highs, and Seroquel for the short-term to help me sleep and hold me over until the other meds worked. Well, they call it the med-go-round for a reason. The average time to stability after first diagnosis is about two years. Almost two years later, I am on Lamictal, Lithium, Depakote, and 100mg of Seroquel. It works all together, and I am stable. So, yes, adding Seroquel is common. In my case, I ran too high for Lamictal alone. I also cycled too much for Lamictal and Lithium so some Depakote was needed. Your story will be different so don’t place too much stock in how meds work for others.

GlaxoSmithKline is alerting healthcare professionals about the dangers of reconstituting Relenza (zanamivir) Inhalation Powder into a liquid and using it in a nebulizer or mechanical ventilator. The powder, which is used in the treatment and prophylaxis of influenza, is only intended to be inhaled using a Diskhaler.

In a recent letter, the company notes that some practitioners have dissolved Relenza Inhalation Powder in various solutions. Using a mechanical ventilator, they then delivered the drug in nebulized form to patients who could not take oral influenza medications or could not inhale the drug using a Diskhaler.

The letter describes the death of a pregnant woman with influenza who was treated with Relenza Inhalation Powder that had been solubilized and administered by mechanical ventilation. The patient’s death was attributed to obstruction of the ventilator, possibly from stickiness caused by lactose in the Relenza Inhalation Powder.

The letter reminds practitioners that the safety, effectiveness and stability of Relenza Inhalation Powder have not been established for nebulization, that this use has not been approved by the FDA, and that this drug should only be administered using the Diskhaler device that comes with it.

FDA Patient Safety News: January 2010

For more information, please see our website:
http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/psn/transcript.cfm?show=94#3

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I was diagnosed with schizophrenia 2005 and its been vaguely under control, but not quite. I relapsed recently when I went off my meds, but I’m on new ones now (Abilify).
The voices are still there, because there’s a 2-3 week period before I reach teh therapeutic dose.
The voices generally talk to each other about me in a derogatory manner, or they tell me to do things that I would really not want to do, or they talk inanely about very random things. I also see things move that shouldn’t be moving, and I see people appear and disappear where they shouldn’t etc.
How do I deal with these things? I’m hoping that they will die down (they never, ever go away completely, even when on meds) in 2-3 weeks’ time. I’m 18 and I will be going back to school on the 8th of Jan, so I need to keep my stress from the voices, and the paranoia from the things that I see at bay. I can’t have people knowing more than they do.
Anything that I could do to keep myself calm when this happens?
Thanks.

Hmm…Id say use mind-over-matter?

I mean, if you see, like, a dragon or something coming right for you (right now I see a dragon made out of trees in my neighbors backyard…Im not a druggie or schizo or anything, just sleep deprived :3 ), then you KNOW that it isnt real. Id say you should try fighting the voices and the appiritions (well, more like stand up to them, I guess). What you have to try to do is convince yourself and the voices that they are ALL just one person (commonly used for multiple personality syndrome, but no harm in giving it a shot, right?), and then see PAST whatever it is you see (such as people disapearing and whatnot).

I dont see why youre so worried about people knowing. I mean, your friends will stick by you if theyre true friends, and others…well, dont give a f uck about them. I bet most wont even bother you cause youre ‘different’ (to ME thats an appealing idear, as Im misanthropic, but if youre more of a people-person, maybe this isnt a good idear). And if they DO bug you, just say that the voices are plotting to murder them and then they should fly away

Can you pcheck some of these physics probs, and help me solve the ones I cannot figure out…thanks so much

1. Find the energy (in MeV) to remove 1 (one) neutron from an O-16 nucleus. (The mass of O-16 is 15.994915 u, O-15 is 15.003065 u, and a single neutron is 1.0086649 u.)
**15.7 MeV?

2. A drug prepared for a patient is tagged with the radioactive isotope Tc-99, which has a half-life of 6.05 h. It is initially prepared with an activity of 1.5 µCi. What is the activity (in µCi) when it is injected 30 minutes later?
**1.42 µCi

3. The half-life of iodine-131, an isotope used in the treatment of thyroid disorders, is 8.04 d. What is the activity (in mCi) of a sample that contains 8.5 x10^13 iodine-131 nuclei?
**2.29 mCi

4. Radioactive isotopes often occur together in mixtures. Suppose a 100g sample contains Ba-131, with a half-life of 12 days and Ca-47, with a half-life of 4.5 days. If there are initially twice as many calcium nuclei as there are barium nuclei, what will be the ratio of calcium to barium 17 days later?A therapeutic dose of phosphorous-32 is ingested by a patient. By monitoring the activity with a radiation detector, it was determined that the initial activity dropped by 50% after 8.0 days. If the "physical" half-life of a sample is 14.3 days, what is the biological half-life of P-32 in this particular patient?

I’ll do 2 through 4.
2. Agree. a(t) = a(0)*2^(-t/Thalf) = 1.41648750208351 µCi
3. Agree. 1 Curie = 3.7E10 events/sec; q is number of nuclei
e-based time constant TC = Thalf / ln(2) = 11.5992681287473 d
Activity (-dq/dt) = q/TC = 8.5E13 / TC = 8.4815376744166E7 events/s;
Curies = -dq/dt / 3.7E10 = 2.29230747957205E-03 Ci
4. 1st Q: Just compute the remaining fractions and take their ratio.
Ca(0)/Ba(0) = 2
Ba(t)/Ba(0) = 2^(-17/12) = 0.37457676921917
Ca(t)/Ca(0) = 2^(-17/4.5) = 0.0729080649735073
Ca(t)/Ba(t) = Ca(0)/Ba(0) * (Ca(t)/Ca(0)) / (Ba(t)/Ba(0)) = 0.389282363268224
2nd Q:
THalf = 8 d; THalf1 = 14.3 d; THalf2 is biological half-life
e-based time constant TCx = THalfx / ln(2)
Decay rates add linearly: dx/dt = -x/TC = -(x/TC1 + x/TC2)
Multiplying by ln(2)/x and rearranging, 1/THalf2 = 1/THalf – 1/THalf1
THalf2 = 18.1587 d
Alternate solution:
Determine the activity scale factor s(1) due to radioactive decay alone.
s(1) = 2^(-8/14.3) = 0.678565243110033
s(1) times the clearing reduction ratio s(2) = 0.5.
s(2) = 0.5/s(1) = 0.736848821947283
THalf2 = -8 / log2(s(2)) = -8 / (ln(0.736848821947283) / ln(2)) = 18.1587 d

Career Search Radiation Therapists Treating cancer in the human body is the principal use of radiation therapy. As part of a medical radiation oncology team, radiation therapists use machines—called linear accelerators—to administer radiation treatment to patients. Linear accelerators, used in a procedure called external beam therapy, project high-energy x rays at targeted cancer cells. As the x rays collide with human tissue, they produce highly energized ions that can shrink and eliminate cancerous tumors. Radiation therapy is someWork environment. Radiation therapists work in hospitals or in cancer treatment centers. These places are clean, well lighted, and well ventilated. Therapists do a considerable amount of lifting and must be able to help disabled patients get on and off treatment tables. They spend most of their time on their feet Radiation therapists generally work 40 hours a week, and unlike those in other health care occupations, they normally work only during the day. However, because radiation therapy emergencies do occur, some therapists are required to be on call and may have to work outside of their normal hours.then positions the patient and adjusts the linear accelerator so that, when treatment begins, radiation exposure is concentrated on the tumor cells. The radiation therapist then develops a treatment plan in conjunction with a radiation oncologist (a physician who specializes in therapeutic radiology), and a dosimetrist (a technician who calculates the dose of radiation that will be used for treatment). The therapist later explains the treatment plan to the patient and answers any questions that the patient may have.Median annual earnings of wage-and-salary radiation therapists were $66,170 in May 2006. The middle 50 percent earned between $54,170 and $78,550. The lowest 10 percent earned less than $44,840, and the highest 10 percent earned more than $92,110. CareerSearch.com

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Grass(Herb) of san juan or hiperico is a natural antidepressant of the quality the prozac or fluoxetina according to the last investigations(researches) in Germany, the (General Central Nutrition) GNC commercializes it as SJW that are 90 capsules with a therapeutic dose from 1 to 3 daily grams, áun the grass(herb) continues being studied to depth and in the long term. Consult this page to see the investigations(researches). Http: // www.saludlandia.com/el-hiperico-e …

Well Jerjes, you are soliciting, phishing, and scamming on Y!A.

Shame on you.

Next time you will be reported.

Dr. Robert Melamede: an expert on Endocannabinoids.

Dr. Melamede says that the Cannabis flower is the most effective and versatile medicine known to humankind. It’s an overall nervous system tune-up.

By our inalienable rights we should be allowed to use it and grow it even for personal therapeutic use, without a doctors approval. It’s good for us. If smoking bothers you than take a dose of the oil.

Website: http://www.uccs.edu/~rmelamed/

http://www.oneradionetwork.com

MP3: http://www.oneradionetwork2.com/mp3/health/healing/melamede_bob_cancer_hemp_cure_june_09.mp3

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Hello. I have the sleep-too-much, eat-too-much kind of depression most of the time, but I also have had periods of hypomania and recently had a full-blown manic episode while coming off Effexor, so the new theory is that I’m bipolar 2. I’m taking Lamictal as a mood stabilizer, but after reaching what I hoped would be a therapeutic dose, I’m still really depressed, with the main symptoms being fatigue, hopelessness, tearfulness, and isolation. I spend a lot of time in bed hiding from the world. My shrink thinks it’s time to add an antidepressant, but she’s not sure which one, and I’m wary because they’ve made me very sleepy in the past.

I think I would feel a lot better if I had the energy to get out of bed and try to get moving toward a better life – i.e. find a job, get going on an exercise program, pursue some of my barely begun projects and hobbies. Any suggestions on what might work best to help get me going?

Thanks!

Here is the thing with people who have bipolar disorder and are on antidepressants… some antidepressants are known to trigger manic episodes so most doctors are cautious about what they antidepressants they prescribe. I can completely relate to the depression you are having and when I am having an episode I wish there was a miracle pill to help me get going on a daily basis but like everyone else I have to wait until the medication gets into my system and begins to work just like everyone else. If your shrink is waiting to decide which antidepressant to put you on she needs to get moving and make a decision. There is no reason why you should wait to start on an antiepressant especially since your daily life is so significantly impacted. If your shrink won’t make a decision seek a second opinion, there is no reason why you should continue to suffer. You might also consider seeing a therapist who can help you deal with the feelings associated with the depression. The both of you could also work on some small (and I stress small) goals that you can work on to break through some of the symptoms, like going for a walk every day or every other day to get you out of the house. Or making sure that you sit down for 10 minutes a day to work on one of your projects. It is easier said then done. But those small accomplishments will also go a long way in helping you to feel like you have moved forward while you are waiting for the meds to kick in. I only make those suggestions because I have had many problems with depression over the years and these are things that have worked for me.

Title: STUDY ON THE PROTECTIVE EFFECT OF METHANOLIC EXTRACT OF MENTHA ARVENSIS L. LEAVES ON HALOPERIDOL INDUCED EXTRAPYRAMIDAL MOVEMENT DISORDERS IN ALBINO RATS

Description:

Anti-psychotics are the drugs used to treat schizophrenia. Typical anti-psychotics like haloperidol produce serious side effects called extrapyramidal movement disorders (EPS)
(catalepsy, tardive dyskinesia, acute dystonia, exploratory behaviour etc.), leading to patient noncompliance and loss of quality of life. These EPS are due to pro-oxidant property of haloperidol which causes oxidative stress induced neuronal damage. So, by the use of anti-oxidants EPS can be reduced.
In the present study, EPS are induced in four groups of albino rats by treating with haloperidol for 21 days,at a dose of 1mg/kg I.P. On the 22nd day three groups of albino rats were treated with MEMA 200mg/kg, 400mg/kg, 600mg/kg respectively. After 30 minutes of administration,haloperidol was injected. The fourth group was treated with haloperidol alone. The therapeutic effect of MEMA on haloperidol induced adverse effects was determined by various methods like hole board test, cataleptic score, and vacuous chewing movements and comparing the (Haloperidol+MEMA) treated groups with Haloperidol treated group.
High dose of MEMA showed a beneficiary effect by reducing the haloperidol induced adverse effects in albino rats. Thus, supplementation of MEMA along with haloperidol showed a protective effect over oxidative stress induced neuronal damage in albino rats.

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Hi–can someone check my answers to these 2 half-life q’s…thanks so so much =)

1.Radioactive isotopes often occur together in mixtures. Suppose a 100g sample contains Ba-131, with a half-life of 12 days and Ca-47, with a half-life of 4.5 days. If there are initially twice as many calcium nuclei as there are barium nuclei, what will be the ratio of calcium to barium 17 days later?
**0.389

2. A therapeutic dose of phosphorous-32 is ingested by a patient. By monitoring the activity with a radiation detector, it was determined that the initial activity dropped by 50% after 8.0 days. If the "physical" half-life of a sample is 14.3 days, what is the biological half-life of P-32 in this particular patient?
**18.2 days

Ca-47
determine k from the half life
ln(2/1) = ln2 = k * t
ln2=k4.5
k = 0.154 day^-1
100 g sample (66.67 g Ca-47 and 33.33 g Ba-131)
ln(66.67/X) = 0.154 * 17days
ln(66.67/X) = 2.618
66.67/X = 13.71
X = 4.865

Ba131
ln2=k12
k=0.05776
ln(33.33/X) = 0.05776 x 17 days
ln(33.33/X) = 0.9820
33.33/X = 2.670
X = 12.48
Ca:Ba = 4.865:12.48 = 0.390